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Ceramide (Brain, Porcine)
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| C130555-25mg | 497156-25-9 | 询价 |
产品介绍
属性
| 存贮条件 | 储存温度 -20°C |
描述
| 应用 |
Ceramide (Brain) has been used as a lipid standard · in ultra performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS) · in liquid chromatography with a hydrophilic interaction column · in liposome preparation to test it effect on human α-synuclein aggregation |
| 产品介绍 | Ceramides comprise sphingoid base attached to fatty acyl chain by an amide bond. They vary in length, saturation and hydroxylation of the fatty acid chain and sphingoid base. Ceramides are synthesized by sphingomyelinase in salvage and de novo synthesis pathway. In brain, ceramide synthases mediate the synthesis of ceramides |
| 生化机理 | Ceramides are signalling molecules which play a key role in cellular events. Ceramides promote β-amyloid synthesis and induce neuronal death. Ceramide levels are associated with pathogenesis of many disease states. Impairment of ceramide metabolism is implicated in Parkinson′s and Alzheimer′s disease. High levels of ceramide is also associated with depression |
| 别名 | Ceramide (Brain);Ceramide (Brain);C18 Ceramide;N-octadecanoyl-D-erythro-sphingosine;N-(octadecanoyl)-sphing-4-enine |
Ceramide (Brain, Porcine)信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Ceramide (Brain, Porcine)报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途