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脂类

N-棕榈酰-D-鞘氨醇

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
N130620-100mg 24696-26-2 询价
N130620-25mg 24696-26-2 询价
N130620-5mg 24696-26-2 询价
产品介绍

  • 分子式 C34H67NO3
  • 分子量537.901
  • Beilstein号
  • EC号
  • MDL号 MFCD00871748
  • PubChem编号

属性

存贮条件 储存温度 -20°C

描述

应用 · as an internal standard in the chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry for myocardial ceramide quantification
· as an internal standard for the ceramide quantification from rat samples using liquid chromatography-mass spectrometry
· to test its effect on mitochondrial stress response in worms
产品介绍 Ceramide comprise sphingosine and fatty acid and belongs to the sphingolipids family
生化机理 C16 Ceramide levels are elevated in chronic alcohol-related liver disease (ALD). In general, ceramide inhibits mitochondrial function and insulin signaling. They are essential component of cell membrane and are involved in lipid raft formation. C16 ceramide based analog (C2-C16 CCPS) is potential anticancer agent used in chemotherapy. The levels of C16 ceramide and its ratio with other ceramides is regarded as a biomarker in predicting coronary artery disease (CAD). It interacts with the DNA-binding domain of tumor suppressor protein p53 and activates p53
别名 (2S,3R,4E)-2-(棕榈酰氨基)-4-十八碳烯-1,3-二醇, N-[(1S,2R,3E)-2-羟基-1-(羟甲基)-3-庚烯-1-基]十六烷酰胺, N-棕榈酰-D-赤型-鞘氨醇, N-棕榈酰-D-鞘氨醇, C16-神经酰胺, C16神经酰胺(d18:1/16:0) ;C16 Ceramide (d18:1/16:0); N-palmitoyl-D-erythro-sphingosine, powder; Cer(d18:1/16:0)

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途