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5-氟-2'-脱氧尿苷

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
F110732-1g 50-91-9 询价
F110732-5g 50-91-9 询价
F110732-500mg 50-91-9 询价
F110732-100mg 50-91-9 询价
F110732-250mg 50-91-9 询价
F110732-25g 50-91-9 询价
产品介绍

  • 分子式 C9H11FN2O5
  • 分子量246.19
  • Beilstein号
  • EC号
  • MDL号 MFCD00006530
  • PubChem编号

属性

熔点 148°C
旋光率 38 ° (C=1, H2O)
敏感性 对热敏感
溶解性 Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.
存贮条件 储存温度 2-8℃
密度 1.6400

描述

应用 5-Fluoro-2′-deoxyuridine has been used as a mitotic inhibitor in schwann cell proliferation, glia proliferation and nonneuronal cells in dorsal root ganglion cultures.
产品介绍 5-Fluoro-2′-deoxyuridine, also called floxuridine elicits DNA-directed cytotoxicity in cancer cells. Floxuridine is effective for treating liver cancer and eliminating virulence of Staphylococcus aureus. Dipeptide prodrugs combination of floxuridine with gemcitabine are more cell permeable and display enhanced anti-proliferative activity. Floxuridine is effective on solid tumours and advanced stage cancers.
生化机理 Antineoplastic drug that acts as a potent inhibitor of thymidylate synthetase Resistance to FUdR can develop in cancer cell cultures, among other means, by low-level Mycoplasma infection.
别名 5-氟-2'-脱氧尿苷 ;氟尿苷,氟脲脱氧核苷,氟苷,5-氟-2'-脱氧脲核苷;2′-Deoxy-5-fluorouridine Floxuridine FUDR 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途