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其它蛋白质/抗原/多肽
6-氨基己酸
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A103971-100g | 60-32-2 | 询价 |
| A103971-2.5kg | 60-32-2 | 询价 |
| A103971-500g | 60-32-2 | 询价 |
产品介绍
- 分子式 C6H13NO2
- 分子量131.17
- Beilstein号 906872
- EC号
- MDL号 MFCD00008238
- PubChem编号
属性
| 熔点 | 204-209°C |
| 敏感性 | 对空气敏感 |
| 溶解性 | Soluble in water (50 mg/ml), ethanol (≥1 mg/ml), methanol (sparingly soluble), ether, and DMSO (≥6 mg/ml). |
| 存贮条件 | 储存温度2-8℃ 充氩保存 |
| 密度 | 1.0420 |
描述
| 应用 | EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature. |
| 产品介绍 | ε-Amino-n-caproic Acid (EACA) is an antifibrinolytic agent shown to enhance the activation of urinary-type and tissue-type plasminogen, while inhibiting plasminogen activation induced by streptokinase through a kringle-dependent mechanism. Believed to act as a lysine analog that competitively inhibits basic carboxypeptidases, and promotes the rapid dissociation of plasmin by inhibiting activation of plasminogen by streptokinase. Incorporation of EACA into short polypeptide fragments with hydrophobic amino acids yielded cytotoxic compounds against MCF-7 breast cells and fibroblast cells. These factors make EACA a potentially useful compound for research in areas such as: oncology, immunology, and in the general elucidation of biochemical pathways. |
| 生化机理 | EACA被报道能够抑制糜蛋白酶、因子VIIA、赖氨酸碳氧基肽酶、纤溶酶，纤溶酶原激活物。赖氨酸类似物。促进纤溶酶快速解离，从而抑制纤溶酶原?的活化以及后续的纤维蛋白溶解。据报告，EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明，EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。 |
| 别名 | 6-氨基己酸 ;氨基己酸,氨己酸,抗血纤溶酸,ε氨基已酸,6-氨基正己酸; EACA;ε-Aminocaproic acid 6-Aminohexanoic acid EACA Hemocaprol |
6-氨基己酸信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于6-氨基己酸报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途