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药物分子
Desloratadine
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| D155989-100MG | 100643-71-8 | 询底价 |
| D155989-1G | 100643-71-8 | 询底价 |
| D155989-250mg | 100643-71-8 | 询底价 |
| D155989-25g | 100643-71-8 | 询底价 |
| D155989-5g | 100643-71-8 | 询底价 |
产品介绍
属性
| 敏感性 | 对热敏感; 对空气敏感 |
| 溶解性 | Soluble in water (partly), ethanol, DMSO (>10 mg/ml), methanol, and chloroform. |
| 存贮条件 | 充氩保存; 储存温度2-8℃ |
描述
| 应用 | Desloratadine是人H1受体拮抗剂。 |
| 产品介绍 | Desloratadine is a potent and selective histamine H1-receptor agonist with a half life of 21-24 hours. Experiments suggest that this compound also exerts antioxidant effects in vitro. Other studies show that H1-receptor binding by desloratadine is reversible and that, over time, desloratadine dissociates from membrane H1-recepters. Desloratadine has also demonstrated the ability to block ICAM-1 upregulation and NFκB activation in primary bronchial and transformed respiratory epithelial cells in vitro. |
| 生化机理 | It is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects. |
| 别名 | 脱羧氯雷他定;地氯雷他定;地洛他定;8-氯-6,11-二氢-11-(4-哌啶烯基)-5H-苯并[5,6]环庚基[1,2-b]吡啶;8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine |
Desloratadine信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Desloratadine报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途