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抗肿瘤剂
6-硫鸟嘌呤
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| T106639-1g | 154-42-7 | 询价 |
| T106639-25g | 154-42-7 | 询价 |
| T106639-5g | 154-42-7 | 询价 |
产品介绍
- 分子式 C5H5N5S
- 分子量167.19
- Beilstein号 157765
- EC号 205-827-2
- MDL号 MFCD00233553
- PubChem编号 24890748
属性
| 熔点 | 360°C |
描述
| 应用 | 抗肿瘤。 |
| 产品介绍 | 6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein. |
| 生化机理 |
Antimetabolite used in the treatment of leukemias. Competes with hypoxanthine and guanine for the enzyme hypoxanthine-guanine phosphoribosyltransferase, which catalzyes a critical step in the generation of purine nucleotides. Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia. |
| 别名 | 2-氨基-6-巯基嘌呤; 6-硫代鸟嘌呤; 2-氨基-6-巯嘌呤;2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol; 6-Mercaptoguanine |
6-硫鸟嘌呤信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于6-硫鸟嘌呤报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途