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犬尿喹啉酸
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| K120012-1g | 492-27-3 | 询底价 |
| K120012-250mg | 492-27-3 | 询底价 |
| K120012-5g | 492-27-3 | 询底价 |
产品介绍
- 分子式 C10H7NO3
- 分子量189.17
- Beilstein号 147451
- EC号 207-751-5
- MDL号 MFCD00006753
- PubChem编号 24277986
属性
| 熔点 | 275°C |
| 溶解性 | Soluble in water (partly), hot alcohol, DMSO (75 mM), 0.1 M NaOH (50 mg/ml), and methanol. |
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | An antagonist of NMDA and AMPA/kainate receptors |
| 产品介绍 | Kynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has been noted to affect calcium mobilization and inositol phosphatase synthesis and may indicate potential signaling functions by Kynurenic acid via the GPR35 receptor. Additionally reported to be a broad spectrum, excitatory amino acid (EAA) antagonist. Other studies have reported that Kynurenic acid acts as an antagonist to mammalian ionotropic glutamate receptors especially NMDA (N-methyl-D-aspartate receptors).Kynurenic acid is an inhibitor of AChR α7, GluR and GlyR. |
| 别名 | 4-羟基-2-喹啉甲酸;4-羟基喹啉-2-甲酸;犬尿喹啉酸水合物;4-羟基喹啉-2-羧酸水合物;4-Hydroxyquinaldic Acid; 4-Hydroxyquinoline-2-carboxylic Acid; Kynurenic Acid Hydrate; 4-Hydroxyquinaldic Acid Hydrate; |
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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途