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牛促肾上腺皮质激素释放激素
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| C118797-1mg | 92307-52-3 | 询价 |
| C118797-5mg | 92307-52-3 | 询价 |
产品介绍
- 分子式 C206H340N60O63S
- 分子量4697.33
- MDL号 MFCD00081537
属性
| 存贮条件 | 储存温度:-20°C |
描述
| 产品介绍 | 氨基酸序列 Ser-Gln-Glu-Pro-Pro-Ile-S?er-Leu-Asp-Leu-Thr-Phe-Hi?s-Leu-Leu-Arg-Glu-Val-Leu?-Glu-Met-Thr-Lys-Ala-Asp-?Gln-Leu-Ala-Gln-Gln-Ala-H?is-Asn-Asn-Arg-Lys-Leu-Le?u-Asp-Ile-Ala Corticotropin Releasing Factor,bovine, (C206H340N60O63S1), a peptide with the sequence H2N-SQEPPISLDLTFHLLREVLEMTKADQLAQQAHNNRKLLDIA-amide, MW= 4697.4. Corticotropin-releasing hormone (CRH) also known as corticotropin-releasing factor (CRF) is a peptide hormone and neurotransmitter involved in the stress response. It belongs to corticotropin-releasing factor family(1). Its main function is the stimulation of the pituitary synthesis of ACTH.Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Increased CRH production has been observed to be associated with Alzheimer's disease and major depression(2), and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to being produced in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta, CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition. |
| 生化机理 | CRF是一种是由垂体前叶释放促肾上腺皮质激素和内啡肽的下丘脑肽。在中枢神经系统中它也是一种神经递质，涉及自主神经和内分泌对刺激的反应。 |
| 别名 | CRF, CRH;CRF, CRH |
牛促肾上腺皮质激素释放激素信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于牛促肾上腺皮质激素释放激素报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途