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细胞信号转导
血管紧张素II
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
A107852-5mg | 4474-91-3 | 询底价 |
A107852-10mg | 4474-91-3 | 询底价 |
A107852-25mg | 4474-91-3 | 询底价 |
产品介绍
- 分子式 C50H71N13O12
- 分子量1046.18
- Beilstein号
- EC号
- MDL号
- PubChem编号 24891466
属性
敏感性 | 热敏感 |
溶解性 | Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml). |
存贮条件 | -20℃保存 |
密度 | 1.4300 |
描述
应用 | A peptide involved in the regulation of blood pressure |
产品介绍 | Angiotensin II plays an important role in the regulation of blood pressure and has strong vasoconstrictive effects. It also stimulates the release of aldosterone from the adrenal gland and inhibits adenylate cyclase activity in spontaneously hypertensive rats. Angiotensin II increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase (MYLK). It also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons and activates JAK2 in smooth muscle cells. Furthermore, angiotensin II activates FAK (p125FAK) and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. It also activates c-Src (p60c-src), ERK1/2, JNK, and p38α (p38 MAP Kinase) in vascular smooth muscle cells. The amino acid sequence Asp-Arg-Val-Tyr-Ile-His-Pro-Phe |
别名 | ;Hypertensin II; Ang II; DRVYIHPF; |
血管紧张素II信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于血管紧张素II报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途