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细胞裂解和提取物

桦木脑

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

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产品参数
货号 CAS号 价格 操作
B129170-1g 473-98-3 面议 询底价
B129170-25g 473-98-3 面议 询底价
B129170-5g 473-98-3 面议 询底价
B129170-100g 473-98-3 面议 询底价
B129169-20mg 473-98-3 ¥135.00 询底价
产品介绍

属性

熔点 256-257°C
存贮条件 储存温度:2-8°C

描述

应用 A triterpene with a pentacyclic ring structure.It can be used in the preparation of betulinic acid,which shows anti-HIV, antimalarial and anti-inflammatory activities.
生化机理 Betulin is a triterpene with a pentacyclic ring structure and hydroxyl groups in positions C3 and C28. Studies indicate that Betulin can effect intracellular signaling in ethanol-induced liver cells via inhibiting ROS, TNFα and TNFβ. In human cancer cells Betulin can induce mitochondrial cytochrome C release in human cancer cells, which results in apoptosis. Alternate studies on mice show that Betulin binds to melanocortin receptors and antagonizes the release of cAMP generation in mouse melanoma cells. Furthermore, Betulin has protective effects against cadmium induced apoptosis in human hepatoma cell lines. This occurs by inhibiting the activation of ROS, blocking Bid activation and suppressing the mitochondrial pathway.
别名 白桦脂醇;桦木醇Lup-20(29)-ene-3β,28-diol

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途