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细胞裂解和提取物

血根碱水合物

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

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产品参数
货号 CAS号 价格 操作
S101540-250mg 5578-73-4 ,2447-54-3 面议 询底价
S101540-50mg 5578-73-4 ,2447-54-3 面议 询底价
S101539-20mg 5578-73-4 ¥398.00 询底价
产品介绍

  • 分子式 C20H14ClNO4 · xH2O
  • 分子量367.78(anhydrous basis)
  • Beilstein号
  • EC号
  • MDL号 MFCD00012126
  • PubChem编号

属性

熔点 277-280°C
溶解性 Soluble in methanol, water (slightly), DMSO (10 mM), and ethanol (5 mM).

描述

应用 一个具有抗菌,消炎,抗氧化性能的天然产物。有抑制肿瘤细胞株扩增和促凋亡作用。
A benzophenanthridine alkaloid and potent, noncompetitive Na+/K+-and Mg2++-ATPase inhibitor
产品介绍 Sanguinarine chloride is a benzophenanthridine alkaloid and potent, noncompetitive sodium/Potassium-ATPase Protein Inhibitors (Na+/K+ ATPase) inhibitor with anticancer properties. This product has been observed to induce apoptosis in cultured C6 rat glioblastoma cells potentially via a downregulative ability of extracellular singal-regulated and Akt signaling pathways. It is reported that sanguinarine also inhibits protein phosphatase 2C (PP2) and induces human promyelocytic leukemia cell line HL60 apoptosis through the phosphorylation of p38, a PP2Cα substrate associated with caspase-3/7 activity. This compound posesses antimicrobial and anti-plaque qualities. Sanguinarine chloride is an inhibitor of MKP-1 and PP2. Isolated from the leaves and stems of Macleaya cordata and M. microcarpa.
备注 CAS Number: 5578-73-4 (anhydrous),Formula weight and CAS # are for anhydrous basis.
别名 氯化血根碱;血根碱盐酸盐

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途