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Lorcaserin HCl
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
| 货号 | CAS号 | 价格（元） | 操作 |
|---|---|---|---|
| L129791-50mg | 846589-98-8 | 129 | 询价 |
| L129791-1g | 846589-98-8 | 699 | 询价 |
| L129791-250mg | 846589-98-8 | 289 | 询价 |
| L129791-5g | 846589-98-8 | 2399 | 询价 |
属性
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | Lorcaserin HCl是一种选择性的人源5-HT2C受体完全激动剂，Ki值为15 nM |
| 生化机理 |
BELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor?agonist?for oral administration used for chronic weight management. Lorcaserin is a highly selective 5-HT2C receptor agonist developed for the treatment of obesity. In rats, lorcaserin led to dose-dependent wt. loss. Lorcaserin proved safe and well tolerated in healthy volunteers and obese patients. In a phase II clin. study, patients administered 20 mg/day lorcaserin achieved an av. wt. loss of 3.6 kg (7.9 lbs), which was significantly greater than the av. wt. loss of 0.3 kg (0.7 lbs) in the placebo group. A phase III clin. trial is ongoing to evaluate the long-term safety and efficacy of lorcaserin in patients with obesity. |
| 别名 | 绿卡色林盐酸盐; (R)-8-氯-1-甲基-2,3,4,5-四氢-1H-3-苯并氮杂卓盐酸盐;(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途