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3,3'-亚甲基二吲哚

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 价格(元) 操作
D129118-25g 1968-05-4 699 询价
D129118-500g 1968-05-4 6799 询价
D129118-5g 1968-05-4 219 询价
D129118-100g 1968-05-4 1949 询价
产品介绍

属性

熔点 165.0-171.0°C
存贮条件 储存温度 2-8°C

描述

应用 An antineoplastic agent that activates Chk 2 and cytochrome p450
产品介绍 3,3'-Diindolylmethane is an anticancer and antineoplastic agent. 3,3'-Diindolylmethane induces apoptosis in human cancer cells. 3,3'-Diindolylmethane is also an activator of CYP (cytochrome P450) and Chk2 (checkpoint kinase 2) as well as a partial agonist of aryl hydrocarbon receptor (Ah Receptor). The compound is a dimer of indole-3-carbinol.
生化机理 Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol.It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells.DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor.The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.
别名 二(3,3'-吲哚基)甲烷;3,3'-二吲哚甲烷;DIM;Di-3-indolylmethane; Plant Indole; 3,3’-Methylenediindole;DIM

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途