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杂环砌块
5-氯-8-羟基-7-碘喹啉
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 价格 | 操作 |
|---|---|---|---|
| C123531-50g | 130-26-7 | ￥499.00 | 询底价 |
| C123531-25g | 130-26-7 | ￥299.00 | 询底价 |
| C123531-10g | 130-26-7 | ￥159.00 | 询底价 |
产品介绍
- 分子式 C9H5ClINO
- 分子量305.50
- Beilstein号 153637
- EC号 204-984-4
- MDL号 MFCD00006787
- PubChem编号 24854949
属性
| 熔点 | 175°C |
| 溶解性 | Soluble in DMSO (>25 mg/ml), boiling alcohol ((1:43)), methanol, and chloroform ((1:120)). |
描述
| 应用 | A metal chelating ligand that inhibits certain enzymes related to DNA replication. |
| 产品介绍 | Clioquinol is a member of the hydroxyquinoline family which inhibits certain enzymes related to DNA replication. Clioquinol is a metal chelating ligand which displays protective effects in various neurodegenerative states as well as being a component in antifungal and antiprotozoal agents. It has been shown to modulate amyloid beta-peptide accumulation via upregulation of metalloprotease activity. When co-administered with vitamin B12, Clioquinol rescues lead-induced impairments of synaptic plasticity in an animal models. In recent animal studies Clioquinol has shown to reverse the progression of Parkinson's, Alzheimer's, and Huntington's diseases. Clioquinol has been observed to induce apoptosis in human cancer cell lines by generating free zinc in lysosomes. |
| 别名 | 奎諾仿;氯碘喹啉;氯碘羟喹;5-氯-7-碘-8-羟基喹啉;Clioqinol; 5-Chloro-8-hydroxy-7-iodoquinoline; Iodochlorhydroxyquin; |
5-氯-8-羟基-7-碘喹啉信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于5-氯-8-羟基-7-碘喹啉报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途