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制药/药物/药检标准品
滨蒿内酯
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 价格（元） | 操作 |
|---|---|---|---|
| D101245-10mg | 120-08-1 | 799 | 询价 |
| D101245-20mg | 120-08-1 | 1199 | 询价 |
产品介绍
- 分子式 C11H10O4
- 分子量206.19
- EC号 204-369-0
- MDL号 MFCD00006871
- PubChem编号 24855271
属性
| 熔点 | 143-145°C |
| 溶解性 | Soluble in DMSO (15 mg/ml), and water (partly miscible). |
| 密度 | 1.2480 |
描述
| 应用 | An agent that can up-regulate the expression and activate CAR |
| 产品介绍 | Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation through activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells. |
| 别名 | 蒿属香豆素Scoparone;6,7-Dimethylesculetin;6,7-Dimethoxy-2H-chromen-2-one;6,7-Dimethoxy-2-benzopyrone |
滨蒿内酯信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于滨蒿内酯报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途