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壬二酸,123-99-9,10mM in DMSO
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 总代理 | 中国 | 现货 |
性能特点
Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity. It is known for it
货号 | 规格 | CAS号 | 价格 | 操作 |
---|---|---|---|---|
A421035-1ml | 1ml | 123-99-9 | ¥205.90 | 询底价 |
中文名:壬二酸
英文名:Azelaic acid
中文别名:杜鹃花酸|1,7-庚二甲酸
英文别名:azelaic acid|NONANEDIOIC ACID|123-99-9|Finacea|Anchoic acid|Azelex|Lepargylic acid|1,7-Heptanedicarboxylic acid|Skinoren|1,9-Nonanedioic acid|Heptanedicarboxylic acid|n-Nonanedioic acid|Emerox 1110|Emerox 1144|azelate|acide azelaique|acidum azelaicum|Fine
纯度:10mM in DMSO
货号:A421035
Cas号:123-99-9
存储温度:-80℃储存
产品介绍:
Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity. It is known for it’s anti acne activity in vitro. Azelaic acid directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and upregulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARν is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途