己酮可可碱，6493-05-6，>98.0%

中文名：己酮可可碱

英文名：Pentoxifylline

中文别名：3,7-二甲基-1-(5-氧代己基)黄嘌呤|3,7-二氢-3,7-二甲基-1-(5-氧代己基)-1H-嘌呤-2,6-二酮|1-(5-氧代己基)可可碱

英文别名：pentoxifylline|Trental|6493-05-6|Oxpentifylline|Pentoxifyllin|Pentoxyphylline|Torental|Pentoxiphyllium|Vazofirin|Dimethyloxohexylxanthine|3,7-Dimethyl-1-(5-oxohexyl)xanthine|Pentoxiphyllin|Pentoxiphylline|Pentoxyfylline|1-(5-Oxohexyl)theobromine|Rentylin|

纯度：>98.0%

货号：P160702

Cas号：6493-05-6

存储温度：-20°C储存

产品介绍：

Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor. Target: PDE Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity. In addition, pentoxifylline improves red blood cell deformability, reduces blood viscosity and decreases the potential for platelet aggregation and thrombus formation. Pentoxifylline is also an antagonist at adenosine 2 receptors . Pentoxifylline is generally well tolerated. Based on the totality of the available evidence, it is possible that pentoxifylline could have a place in the treatment of IC as a means of improving walking distance and as a complimentary treatment assuming all other essential measures such as lifestyle change, exercise and treatment for secondary prevention have been taken into account . Pentoxifylline reduce AST and ALT levels and may improve liver histological scores in patients with NALFD/NASH, but did not appear to affect cytokines. Large, prospective, and well-designed randomized, controlled studies are needed to address this issue .Pentoxifylline是竞争性非选择性磷酸二酯酶（PDE）抑制剂

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途