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奥利司他,96829-58-2,>97.0%(HPLC)
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 总代理 | 中国 | 现货 |
性能特点
Lipase Inhibitor, THL (Tetrahydrolipstatin), is a compound that has been shown to rapidly inacti
货号 | 规格 | CAS号 | 价格 | 操作 |
---|---|---|---|---|
O159936-100mg | 100mg | 96829-58-2 | ¥29.90 | 询底价 |
O159936-1g | 1g | 96829-58-2 | ¥74.90 | 询底价 |
O159936-100g | 100g | 96829-58-2 | ¥1,534.90 | 询底价 |
O159936-25g | 25g | 96829-58-2 | ¥461.90 | 询底价 |
O159936-5g | 5g | 96829-58-2 | ¥129.90 | 询底价 |
O159936-250mg | 250mg | 96829-58-2 | ¥30.90 | 询底价 |
中文名:奥利司他
英文名:Orlistat
中文别名:奧利司他|(-)-四氢脂抑素
英文别名:orlistat|96829-58-2|Tetrahydrolipstatin|Xenical|Alli|Orlipastat|(-)-Tetrahydrolipstatin|Orlipastatum [INN-Latin]|Ro-18-0647|Ro 18-0647/002|Orlistat (Alli, Xenical)|(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate|
纯度:>97.0%(HPLC)
货号:O159936
Cas号:96829-58-2
存储温度:-20°C储存,充氩
产品介绍:
Lipase Inhibitor, THL (Tetrahydrolipstatin), is a compound that has been shown to rapidly inactivate lipoprotein lipase (LPL). This agent has been found to bind both subunits of LPL, induce tetramerisation, and cause local conformational changes. The exception to lipase inhibition capacities of THL is phospholipase A2, which is not affected by THL. Mechanistic studies sμggest that THL inhibits the thioesterase domain of fatty acid synthase (FAS) and as a result halts cell proliferation and causes cell apoptosis. More detailed experiments show that gradually THL affects the retinoblastoma protein pathway and leads to cell-cycle arrest at G1/S boundary. Lipase Inhibitor, THL is an inhibitor of pancreatic and gastric lipase, as well as carboxyl ester lipase (CEL) and diacylglycerol lipase-α (DAGLα). Lipase Inhibitor, THL also activates caspase-3.Orlistat是一种通用的脂肪酶抑制剂,作用于人体十二指肠液的PL,IC50为122 ng/ml。
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途