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醋酸普兰林肽,196078-30-5,98%
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 总代理 | 中国 | 现货 |
性能特点
product description: Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormo
货号 | 规格 | CAS号 | 价格 | 操作 |
---|---|---|---|---|
P334885-2.5mg | 2.5mg | 196078-30-5 | ¥2,369.00 | 询底价 |
P334885-25mg | 25mg | 196078-30-5 | ¥2,059.90 | 询底价 |
P334885-100mg | 100mg | 196078-30-5 | ¥5,149.90 | 询底价 |
P334885-50mg | 50mg | 196078-30-5 | ¥3,295.90 | 询底价 |
P334885-5mg | 5mg | 196078-30-5 | ¥720.90 | 询底价 |
中文名:醋酸普兰林肽
英文名:Pramlintide Acetate
英文别名:Tripo-amylin Acetate Hydrate; AC-137 Acetate Hydrate, Symlin Acetate Hydrate
纯度:98%
货号:P334885
Cas号:196078-30-5
存储温度:-20°C储存
产品介绍:
product description:
Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human amylin receptor 1a (AMY1a), AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively). Pramlintide inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner. In vivo, pramlintide (200 pg/kg) reduces brain levels of amyloid-β (1-40) and increases spontaneous alternation in the Y-maze in the Tg2576 transgenic mouse model of Alzheimer's disease.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途