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根赤壳菌素,12772-57-5,98%
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 总代理 | 中国 | 现货 |
性能特点
Radicicol, a microbial cell differentiation modulator originally extracted from Neocosmospora te
货号 | 规格 | CAS号 | 价格 | 操作 |
---|---|---|---|---|
R102391-5mg | 5mg | 12772-57-5 | ¥3,810.90 | 询底价 |
R102391-1mg | 1mg | 12772-57-5 | ¥1,029.90 | 询底价 |
中文名:根赤壳菌素
英文名:Radicicol
中文别名:根赤壳霉素
英文别名:radicicol|Monorden|12772-57-5|Monorden A|(+)-Monorden A|I60EH8GECX|CHEMBL414883|CHEBI:556075|NSC-294404|(1aR,2Z,4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione|Monorderne|RDC|Ra
纯度:98%
货号:R102391
Cas号:12772-57-5
存储温度:-20°C储存,充氩
产品介绍:
Radicicol, a microbial cell differentiation modulator originally extracted from Neocosmospora tenuicristata, has been shown to inhibit proliferation and plasminogen activator production by vascular endothelial cells. Radicicol inhibits the expression of Cox-2 (IC50 = 27 nM) without affecting Cox-1 expression in LPS-stimulated macrophages. It is also a potent inhibitor of Hsp90. Experiments sμggest that radicicol reduces the intracellular level of autophosphorylation of p60v-src as well as other tyrosine-phosphorylated proteins via inhibition of SRC kinases. In addition, radicicol has demonstrated the ability to inhibit K-ras signaling pathway which includes phosphorylation of Raf-1, MAPKK, and MAPK.A potent inhibitor of Hsp90, SRC, and Cox-2
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途