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利伐沙班,366789-02-8,≥99%
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 总代理 | 中国 | 现货 |
性能特点
Rivaroxaban is an oral, direct inhibitor of Factor X, being developed for the prevention and tre
货号 | 规格 | CAS号 | 价格 | 操作 |
---|---|---|---|---|
R125138-10mg | 10mg | 366789-02-8 | ¥29.90 | 询底价 |
R125138-50mg | 50mg | 366789-02-8 | ¥30.90 | 询底价 |
R125138-1g | 1g | 366789-02-8 | ¥102.90 | 询底价 |
R125138-5g | 5g | 366789-02-8 | ¥333.90 | 询底价 |
R125138-250mg | 250mg | 366789-02-8 | ¥55.90 | 询底价 |
R125138-25g | 25g | 366789-02-8 | ¥1,134.90 | 询底价 |
中文名:利伐沙班
英文名:Rivaroxaban
中文别名:利伐沙班
英文别名:B01AF01|1429742-50-6|2-Thiophenecarboxamide, 5-chloro-N-(((5S)-2-oxo-3-(4-(3-oxo-4-morpholinyl)phenyl)-5-oxazolidinyl)methyl)-|2w26|9NDF7JZ4M3|Q420262|Xarelto|MFCD11974010|N-Smc-carboxylate|L-Glutatione|RIVAROXABAN [ORANGE BOOK]|MLS006010027|Rivaroxaban|R
纯度:≥99%
货号:R125138
Cas号:366789-02-8
存储温度:-20°C储存
产品介绍:
Rivaroxaban is an oral, direct inhibitor of Factor X, being developed for the prevention and treatment of arterial and venous thrombosis with a Ki of 0.4 nM. Rivaroxaban also inhibits prothrombinase activity (IC50 = 2.1 nM). Rivaroxaban also shows a similar affinity to purified human (IC50 = 0.7 nM) and rabbit Factor X (IC50 = 0.8 nM), but a lesser potency against purified rat Factor X (IC50 = 3.4 nM). Endogenous human and rabbit Factor X in plasma is inhibited to a similar extent by Rivaroxaban (IC50 = 21 nM and 21 nM, respectively), while 14-fold higher concentrations are required in rat plasma (IC50 = 290 nM). Rivaroxaban exhibits high permeability and polarized transport across Caco-2 cells as a substrate of the P-gp, but exhibits no inhibitory effect on P-gp-mediated drμg transport up to concentrations of 100 μM in vitro.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途