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甲苯磺丁脲，64-77-7，10mM in DMSO
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 总代理 | 中国 | 现货 |
性能特点
Tolbutamide is a sulfonylurea agonist for secretion of insulin by beta-cells. In rat pancreatic
| 货号 | 规格 | CAS号 | 价格 | 操作 |
|---|---|---|---|---|
| T425282-1ml | 1ml | 64-77-7 | ￥479.90 | 询底价 |
中文名：甲苯磺丁脲
英文名：Tolbutamide
中文别名：甲糖宁
英文别名：NSC 23813|Orinase|Tolylsulfonylbutylurea|CAS-64-77-7|tolbutamide|U 2043|3-butyl-1-(4-methylbenzenesulfonyl)urea|DTXCID801359|N-4-Methylbenzolsulfonyl-N-butylurea|SMR000058363|Tolbutamida|Tolbutamidum [INN-Latin]|1-p-Toluenesulfonyl-3-butylurea|Diabuton|DT
纯度：10mM in DMSO
货号：T425282
Cas号：64-77-7
存储温度：-80℃储存
产品介绍：
Tolbutamide is a sulfonylurea agonist for secretion of insulin by beta-cells. In rat pancreatic beta-cells cultured in the presence of Tolbutamide displayed increased numbers of beta-cells in a dose responsive manner with beta-cell numbers doubling at 100 μg/ml of Tolbutamide. The compound displayed inhibitory action towards beta-cells at concentrations greater than 100 μg/ml. In addition in the presence of low glucose concentrations Tolbutamide’s cytotrophic action was inhibited. On isolated dog pancreas islets Tolbutamide at 180 μM stimulated the release of somatostatin, insulin and glucagon in the absence of glucose. in all situations the loss of Ca2+ eliminated all effects of Tolbutamide. The compound has been observed to mechanistically enhance the secretion of insulin by highly selective amplification of insulin secretory burst mass.
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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途
