HY-N0664 Aucubin | MedChemExpress (MCE)
品牌 | 厂商性质 | 产地 | 货期 | 价格 |
---|---|---|---|---|
MedChemExpress (MCE) | 生产商 | 美国 | 现货 | 2300 |
性能特点
Aucubin 是一种可从许多传统的草药中提取的环烯醚萜苷。Aucubin 具有许多生物学活性,例如抗氧化,抗衰老,抗炎,抗菌,抗纤维化,抗癌,保肝,神经保护和骨保护作用。
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mM * 1 mL | 479-98-1 | ¥473.00 | 询底价 |
5 mg | 479-98-1 | ¥430.00 | 询底价 |
10 mg | 479-98-1 | ¥700.00 | 询底价 |
50 mg | 479-98-1 | ¥2,300.00 | 询底价 |
MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
CAS No. : 479-98-1
MCE 国际站:Aucubin
产品活性:Aucubin 是一种可从许多传统的草药中提取的环烯醚萜苷。Aucubin 具有许多生物学活性,例如抗氧化,抗衰老,抗炎,抗菌,抗纤维化,抗癌,保肝,神经保护和骨保护作用。
研究领域:Anti-infection
作用靶点:Bacterial
In Vitro: Aucubin (0.001-1 μg/mL; pretreated for 30 min) dose-dependently inhibits IgE-induced TNF-α and IL-6 production and expression in RBL-2H3 cells, with IC50s of 0.101 and 0.19 μg/mL, respectively.
?Aucubin (0.01 μg/mL; pretreated for 30 min) inhibits IgE-induced nuclear translocation of p65 subunit of NF-κB and degradation of IκBα in RBL-2H3 cells.
?Aucubin (0.001-1 mM; 12 h) increases PC12 cellular viability and markedly inhbits H2O2-induced apoptotic cell death.
In Vivo: Aucubin (5 mg/kg; i.p. for 15 d) has antioxidant and pancreas-protective effects on rats with streptozotocin-induced diabetes.
?Aucubin (40-200 mg/kg; a single i.p.) exhibits significant protective activity against α-amanitin intoxication in mice.
?Aucubin (5 mg/kg/day; i.p. for 21 d) decreases the breathing frequency, increases the lung dynamic compliance, alleviates lung parenchymal fibrotic changes, and reduces the intrapulmonary collagen disposition and inflammatory injury of BLM-stimulated mice.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途