Diosmetin | 香叶木素 | MedChemExpress (MCE)
品牌 | 厂商性质 | 产地 | 货期 | 价格 |
---|---|---|---|---|
MedChemExpress (MCE) | 生产商 | 美国 | 现货 | 550 |
性能特点
Diosmetin是抑制人CYP1A酶活性的天然类黄酮, 在HepG2细胞的 IC50值为40 μM。
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mM * 1 mL | 520-34-3 | ¥550.00 | 询底价 |
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Diosmetin
CAS No. : 520-34-3
MCE 国际站:Diosmetin
产品活性:Diosmetin是抑制人CYP1A酶活性的天然类黄酮, 在HepG2细胞的 IC50值为40 μM。
研究领域:Metabolic Enzyme/Protease
作用靶点:Cytochrome P450
In Vitro: Diosmetin inhibits cell proliferation in HepG2 cells in a concentration-dependent manner. Untreated HepG2 cells grow well and are observed to have with normal skeletons, whereas cells treated with diosmetin are distorted and a number of them become round and floating.
In Vivo: Pretreatment with diosmetin significantly reduces serum levels of amylase and lipase; the histological injury; the secretion of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6; myeloperoxidase (MPO) activity, trypsinogen activation peptide (TAP) level, the expression of inducible nitric oxide synthase (iNOS); and the nuclear factor (NF)-κB activation in cerulein-induced acute pancreatitis.
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途