LJ001 | MedChemExpress (MCE)

LJ001 产品活性：LJ001 是一种广谱的具有口服活性的抗病毒活性分子。LJ001 通过与病毒膜结合发挥抗病毒活性。LJ001 抑制 TGEV 和 PDCoV 感染。LJ001 降低 TGEV N 和 PDCoV N 蛋白的表达。 产品来源： https://www.medchemexpress.cn/lj001.html 研究领域：Anti-infection 作用靶点：HCV | HIV In Vitro: LJ001 (0.782- 200 μM; 24 h) shows no significant cytotoxicity with a CC50 value of 146.4 μM for ST cells. LJ001 (12.5 µM; 12, 24 h) inhibits transmissible gastroenteritis virus (TGEV) and porcine deltacoronavirus (PDCoV) infection. LJ001 (12.5 µM; 1, 6,12, 24 h) decreases the TGEV and PDCoV gene mRNA expression in ST cells. LJ001 can inhibit the entry and spread of some enveloped viruses, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), influenza, Ebola, arenaviruses and poxvi ruses. In Vivo: LJ001 (20, 50 mg/kg; oral gavage or i.p.; daily for 7 days) shows no toxicity in mouse. 相关产品：Bioactive Compound Library Plus | Anti-Infection Compound Library | Antiviral Compound Library | Orally Active Compound Library | Anti-Hepatitis C Virus Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Chloroquine | Doxorubicin hydrochloride | 5-Fluorouracil | Resiquimod | Q-VD-OPh | Valproic acid | Panobinostat | Shikonin | Probenecid | Kaempferol | Dimethyl fumarate | Hydroxyurea | Plerixafor | Maraviroc | Birinapant | Baicalin | Honokiol | Flavopiridol | Ribavirin | Deferiprone | Ritonavir | U18666A | Ivermectin | Fasudil Hydrochloride | Ebselen | Rolipram | Lysozyme from chicken egg white | Artemisinin 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途