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快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧! DuP-697 is a highly selective and irreversible inhibitor of cyclooxygenase-2 (COX-2). (COX-2 IC50=10nM, COX-1 IC50=800nM). It is an orally effective anti-inflammatory, analgesic and antipyretic agent which is not ulcerogenic. Inhibition of COX-2 by DuP-697 and other inhibitors exacerbates ischemia-induced myocardial dysfunction in the rabbit. It inhibits angiogenesis and induces apoptosis in human endothelial cells.
Product Specification
Formula: C17H12BrFO2S2
MW: 411.3
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 88149-94-4
Solubility: Soluble in DMSO (10mg/ml) or 100% ethanol (5mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C