Nutlin-3b-分析测试百科网

Nutlin-3b

面议

分子式 C30H30Cl2N4O4 分子量581.49 属性溶解性 DMSO 100 mg/mL Water <1 mg/mL Ethanol 100 mg/mL 存贮条件储存温度-20°C //decorateTable('pr

400-6699-117 转1000

耗材描述

溶解性	DMSO 100 mg/mL Water <1 mg/mL Ethanol 100 mg/mL
存贮条件	储存温度-20°C

产品介绍	Nutlin-3b是MDM2/p53抑制剂，IC50为13.6 μM。
生化机理	Nutlin-3b is a 150-fold less potent (+)-enantiomer of Nutlin-3 as p53 MDM2 antagonist or inhibitor, in comparison with more potent opposite (-)-enantiomer Nutlin-3a. It is useful as a negative control for non-Mdm2 related cellular activities.
别名	Nutlin 3b; 4-[[(4R,5S)-4,5-双(4-氯苯基)-4,5-二氢-2-[4-甲氧基-2-(1-甲基乙氧基)苯基]-1H-咪唑-1-基]羰基]-2-哌嗪酮;Nutlin 3b;4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone