| 应用 |
A selective and high affinity CB1 antagonist. |
| 产品介绍 |
Otenabant (CP-945598) HCl是一种有效的，选择性cannabinoid receptor CB1拮抗剂，Ki为0.7 nM，比作用于人类CB2受体选择性高10，000倍。 |
| 备注 |
CP-945598 HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1. |
| 生化机理 |
CP 945598 hydrochloride is a selective and high affinity CB1 antagonist. This compound has been shown to have low affinity for CB2 receptors |
| 别名 |
奥特那班盐酸盐; 1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-4-piperidinecarboxamide hydrochloride; 1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride; CP 945598-01; Otenabant hydrochloride;Otenabant HCl |
