Tadalafil
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分子式 C22H19N3O4 分子量389.4 Beilstein号 EC号 200-835-2 MDL号 PubChem编号 属性 溶解性 Soluble in DMSO (78 mg/ml at 25 °C), methanol, wa
| 货号 | CAS号 | 操作 |
|---|---|---|
| T125358-100mg | 171596-29-5 | 询底价 |
| T125358-1g | 171596-29-5 | 询底价 |
| T125358-250mg | 171596-29-5 | 询底价 |
| T125358-25g | 171596-29-5 | 询底价 |
| T125358-500mg | 171596-29-5 | 询底价 |
耗材描述
- 分子式 C22H19N3O4
- 分子量389.4
- Beilstein号
- EC号 200-835-2
- MDL号
- PubChem编号
属性
| 溶解性 | Soluble in DMSO (78 mg/ml at 25 °C), methanol, water (< 1 mg/ml at 25 °C), dichloromethane, and ethanol (< 1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A phosphodiesterase 5 inhibitor |
| 产品介绍 | adalafil是一种PDE-5抑制剂，IC50为1.8 nM。 |
| 备注 | Tadalafil is a PDE-5 inhibitor with IC50 of 1.8 nM. |
| 生化机理 | Tadalafil is a potent and selective inhibitor of PDE5A (Phosphodiesterase-5, PDE5). This compound prevents the breakdown of phosphodiesterases, many of which are used as secondary messengers. By preventing the breakdown of these messenger molecules, tadalafil can prolong signal transduction and amplify its effect. |
| 别名 | 西力士; 他地那非; 他达那非; (6R-12aR)-6-(1,3-苯并二噁茂-5-基)-2-甲基-2,3,6,7,12,12a-六氢化吡嗪并[1',2'-1,6]-吡啶并[3,4-b]吲哚-1,4-二酮;(6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1,2:1,6]pyrido[3,4-b]indole-1,4-dione; Cialis; GF 196960; IC 351; ICOS 351; Tildenafil; UK 336017 |
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