| 应用 |
A SCD1 inhibitor and apoptosis inducer. |
| 产品介绍 |
PluriSIn #1 (NSC 14613)是一种stearoyl-coA desaturase 1 (SCD1)抑制剂，选择性消除hPSCs。 |
| 备注 |
PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs. |
| 生化机理 |
PluriSln 1 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1). It is useful for eliminating undifferentiated human pluripotent stem cells (hPSCs) from culture by selectively inducing apoptosis in these cells. Additionally, pluriSln 1 induces endoplasmic reticulum stress, reduces protein synthesis, and prevents teratoma formation in immunocompromised mice models. |
| 别名 |
4-吡啶羧酸 2-苯基酰肼;Isonicotinic acid 2-phenylhydrazide; 4-Pyridinecarboxylic acid 2-phenylhydrazide; NSC 14613;PluriSln 1 |
