Ketoprofen
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分子式 C16H14O3 分子量254.28 EC号 244-759-8 MDL号 MFCD00055790 PubChem编号 24278504 属性 熔点 92-97° 敏感性 对光敏感 溶解性 Soluble in ethanol (
| 货号 | CAS号 | 操作 |
|---|---|---|
| K129331-500g | 22071-15-4 | 询底价 |
| K129331-25g | 22071-15-4 | 询底价 |
| K129331-250g | 22071-15-4 | 询底价 |
| K129331-5g | 22071-15-4 | 询底价 |
| K129331-100g | 22071-15-4 | 询底价 |
耗材描述
- 分子式 C16H14O3
- 分子量254.28
- EC号 244-759-8
- MDL号 MFCD00055790
- PubChem编号 24278504
属性
| 熔点 | 92-97° |
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in ethanol (51 mg/ml at 25 °C), DMSO (51 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), DMF (≥20 mg/ml), and PBS (pH 7.2) (≥0.5 mg/ml). |
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | An inhibitor of Cox-1 and Cox-2. |
| 产品介绍 | Ketoprofen 是一种非选择性的NSAID，作用于人重组COX-1和COX-2， IC50分别为0.5 μM和2.33 μM。 |
| 备注 | Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively. |
| 生化机理 | Ketoprofen is a non-selective NSAID which inhibits both human recombinant Cox-1 (IC50 of 0.5 μM) and Cox-2 (IC50 of 2.33 μM). Ketoprofen is used for its antipyretic, analgesic, and anti-inflammatory properties by inhibiting Cox-1 and Cox-2 (cyclooxygenase-1 and -2) enzymes reversibly, which decreases production of pro-inflammatory prostaglandin precursors. |
| 别名 | 2-(3-苯甲酰苯基)丙酸;酮基布洛芬;α-甲基-3-苯甲酰基苯乙酸;酮洛芬;2-(3-Benzoylphenyl)propionic acid |
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