K129331-25gKetoprofen
面议
- 阿拉丁
- 生产商
- K129331-25g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C16H14O3
- 分子量254.28
- EC号 244-759-8
- MDL号 MFCD00055790
- PubChem编号 24278504
属性
熔点 | 92-97° |
敏感性 | 对光敏感 |
溶解性 | Soluble in ethanol (51 mg/ml at 25 °C), DMSO (51 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), DMF (≥20 mg/ml), and PBS (pH 7.2) (≥0.5 mg/ml). |
存贮条件 | 储存温度2-8℃ |
描述
应用 | An inhibitor of Cox-1 and Cox-2. |
产品介绍 | Ketoprofen 是一种非选择性的NSAID,作用于人重组COX-1和COX-2, IC50分别为0.5 μM和2.33 μM。 |
备注 | Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively. |
生化机理 | Ketoprofen is a non-selective NSAID which inhibits both human recombinant Cox-1 (IC50 of 0.5 μM) and Cox-2 (IC50 of 2.33 μM). Ketoprofen is used for its antipyretic, analgesic, and anti-inflammatory properties by inhibiting Cox-1 and Cox-2 (cyclooxygenase-1 and -2) enzymes reversibly, which decreases production of pro-inflammatory prostaglandin precursors. |
别名 | 2-(3-苯甲酰苯基)丙酸;酮基布洛芬;α-甲基-3-苯甲酰基苯乙酸;酮洛芬;2-(3-Benzoylphenyl)propionic acid |
标识符号 | GHS06 |
信号词 | Danger |
危害声明 | H301-H315-H319-H335 |
警示性声明 | P261-P301 + P310-P305 + P351 + P338 |
个人防护设备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
RTECS | UE7570000 |
WGK德国 | 3 |
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