Etodolac
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分子式 C17H21NO3 分子量287.35 Beilstein号 EC号 MDL号 MFCD00133313 PubChem编号 24278407 属性 熔点 148°C 敏感性 对热和光线敏感 溶解性 Soluble in DMSO
| 货号 | CAS号 | 操作 |
|---|---|---|
| E129317-25g | 41340-25-4 | 询底价 |
| E129317-1g | 41340-25-4 | 询底价 |
| E129317-5g | 41340-25-4 | 询底价 |
| E129317-100g | 41340-25-4 | 询底价 |
耗材描述
- 分子式 C17H21NO3
- 分子量287.35
- Beilstein号
- EC号
- MDL号 MFCD00133313
- PubChem编号 24278407
属性
| 熔点 | 148°C |
| 敏感性 | 对热和光线敏感 |
| 溶解性 | Soluble in DMSO (100 mM), and ethanol (100 mM). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 产品介绍 | Etodolac 是COX抑制剂，IC50为53.5 nM。 |
| 备注 | Etodolac (Lodine) is a COX inhibitor with an IC50 of 53.5 nM. |
| 生化机理 | Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of aberrant crypt foci and tumors in colitis-induced tumorigenesis in rats. Etodolac is an inhibitor of Cox-1. |
| 别名 | 依托度酸; 1,8-二乙基-1,3,4,9-四氢吡喃[3,4-b]吲哚-1-乙酸;1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid;Etodlic Acid |
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