Fluticasone propionate-分析测试百科网

Fluticasone propionate

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：3
近期咨询：0

分子式 C25H31F3O5S 分子量500.57 Beilstein号 EC号 MFCD00866007 MDL号 MFCD00866007 PubChem编号属性熔点 275°C(lit.) 溶解性 DMSO 100 mg/mL W

上海阿拉丁生化科技股份有限公司

上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
F129894-100mg	80474-14-2	询底价
F129894-1g	80474-14-2	询底价
F129894-5g	80474-14-2	询底价

耗材描述

分子式 C₂₅H₃₁F₃O₅S
分子量500.57
Beilstein号
EC号 MFCD00866007
MDL号 MFCD00866007
PubChem编号

属性

熔点	275°C(lit.)
溶解性	DMSO 100 mg/mL Water <1 mg/mL Ethanol 5 mg/mL

描述

应用	A high-affinity, selective glucocorticoid receptor agonist.
产品介绍	Fluticasone propionate 是一种合成的皮质类固醇，是Fluticasone的衍生物，用于治疗哮喘和过敏性鼻炎（花粉症）。
备注	Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever).
生化机理	Fluticasone propionate is a high affinity, selective glucocorticoid receptor (GR) agonist (Kd = 0.5 nM). Fluticasone propionate potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC50 = 3.7 nM) in vitro. Fluticasone propionate is a lipophilic anti-inflammatory agent derived from flumethasone.
别名	丙酸氟替卡松;氟替卡松丙酸酯;6,9-二氟-11羟基甲基氧代(氧代丙氧基)雄甾,二烯硫代羧酸-S-氟甲酯;(6α,11β,16α,17α)-6,9-二氟-11-羟-16-甲基-3-氧代-17-(1-氧代丙氧基)-雄甾-1,4-二烯-17-硫代羧酸 S-(氟甲基)酯;Flonase; Veramyst;(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester;S-Fluoromethyl-6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carbothioate;

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