耗材描述

• 分子式 C₂₀H₁₅Cl₃N₂OS·HNO₃
• 分子量500.78
• Beilstein号
• EC号
• MDL号
• PubChem编号

属性

熔点	163-165 °C
溶解性	Soluble in DMSO (20 mg/ml), and methanol.
存贮条件	储存温度-20°C

描述

生化机理

Sertaconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Sertaconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis

别名

硝酸舍他康唑; 1-(2-((7-氯苯并(b)噻吩-3-基)甲氧基)-2-(2,4-二氯苯基)乙基)-1H-咪唑硝酸盐;1-[2-[(7-Chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate;Ertaczo; Dermofix; Konzert; FI7056

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