耗材描述

• 分子式 C₁₅H₁₂N₂OS₂
• 分子量300.39

属性

溶解性	Soluble in DMSO (60 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
存贮条件	储存温度 2-8°C

描述

应用	A selective inhibitor of E-selectin and ICAM-1 expression.
产品介绍	A-205804是一种强有效和选择性E-selectin和ICAM-1表达抑制剂， IC50分别为20 nM和25 nM。
备注	A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
生化机理	A 205804 is a selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-α-induced E-selectin, ICAM-1 and VCAM-1 expression respectively). Effective inhibitor of cell-cell adhesion in an in vitro flow experiment.
别名	4-[(4-甲基苯基)硫基]噻吩并[2,3-c]吡啶-2-甲酰胺;A 205804;4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide;A 205804

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