Istradefylline
面议
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分子式 C20H24N4O4 分子量384.43 Beilstein号 EC号 MDL号 MFCD00928421 PubChem编号 属性 溶解性 DMSO 6 mg/mL Water <1 mg/mL Ethanol <1
| 货号 | CAS号 | 操作 |
|---|---|---|
| I125338-25mg | 155270-99-8 | 询底价 |
| I125338-5mg | 155270-99-8 | 询底价 |
| I125338-100mg | 155270-99-8 | 询底价 |
耗材描述
- 分子式 C20H24N4O4
- 分子量384.43
- Beilstein号
- EC号
- MDL号 MFCD00928421
- PubChem编号
属性
| 溶解性 |
|
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | A selective A(2A) antagonist used to study parkinson’s disease in vitro |
| 产品介绍 | Istradefylline(KW6002)是口服活性的腺苷A2A受体拮抗剂，Ki为2.2 nM。 |
| 备注 | Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. |
| 生化机理 |
Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist in experimental models of Parkinson's disease. Istradefylline reduces dyskinesia resulting from long-term treatment with classical antiparkinson drugs such as levodopa. Istradefylline is an analog of caffeine. |
| 别名 | 8-((E)-2-(3,4-二甲氧基苯基)乙烯基)-1,3-二乙基-7-甲基嘌呤-2,6-二酮;;KW 6002;KW-6002;KW6002;istradefylline;8-((e)-2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-7-methylpurine-2,6-dione; |
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