OSI-420-分析测试百科网

OSI-420

面议

分子式 C21H21N3O4.HCl 分子量415.87 属性溶解性 DMSO 83 mg/mL Water 2 mg/mL Ethanol <1 mg/mL 存贮条件储存温度-20°C //decorateTable('prod

400-6699-117 转1000

耗材描述

溶解性	DMSO 83 mg/mL Water 2 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

备注	OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
生化机理	OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
别名	2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride;2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride