Amuvatinib (MP-470)-分析测试百科网

Amuvatinib (MP-470)

面议

分子式 C23H21N5O3S 分子量447.52 属性溶解性 DMSO 32 mg/mL Water <1 mg/mL Ethanol <1 mg/mL 存贮条件储存温度-20°C //decorateTable('pro

400-6699-117 转1000

耗材描述

溶解性	DMSO 32 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

应用	A multi-targeted tyrosine kinase inhibitor of PDGF and c-Kit。
产品介绍	Amuvatinib (MP-470)是多靶点抑制剂，对c-Kit(D816H)，PDGFRα(V561D)和FLT3(D835Y)的IC50分别为10 nM，40 nM和81 nM。
生化机理	Amuvatinib is a potent and multi-targeted tyrosine kinase inhibitor that inhibits c-Kit and PDGFα and has been shown to induce apoptosis.
别名	MP-470; MP 470; MP470; HPK 56; N-(1,3-苯并二氧戊环-5-基甲基)-4-苯并呋喃并[3,2-d]嘧啶-4-基-1-哌嗪硫代甲酰胺;Amuvatinib；MP-470; MP 470; MP470; HPK 56；N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide