变蓝菌素
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分子式 C12H17NO3 分子量223.27 Beilstein号 4140423 EC号 241-424-8 MDL号 MFCD00077686 PubChem编号 24892323 属性 敏感性 对光敏感 溶解性 Cerulenin
货号 | CAS号 | 操作 |
---|---|---|
C102399-5mg | 17397-89-6 | 询底价 |
C102399-10mg | 17397-89-6 | 询底价 |
C102399-25mg | 17397-89-6 | 询底价 |
耗材描述
- 分子式 C12H17NO3
- 分子量223.27
- Beilstein号 4140423
- EC号 241-424-8
- MDL号 MFCD00077686
- PubChem编号 24892323
属性
敏感性 | 对光敏感 |
溶解性 | Cerulenin is soluble in DMSO, Methanol, Ethanol, Dichloromethane, Acetone, Benzene and most common solvents. Concentrations up to 20 mg/ml can be achieved. Slightly soluble in H2O. Concentrations up to 0.2 mg/ml are achievable. Not soluble in Petrol Ether |
存贮条件 | 储存温度-20°C,充氩储存 |
密度 | 1.1340 |
描述
应用 | An inhibitor fatty acid and sterol biosynthesis |
产品介绍 | Cerulenin has broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to β-keto-acyl-ACP .synthase blocking the interaction of malonyl CoA. Cerulenin also an inhibits bacterial fatty acid synthesis, acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity. |
生化机理 | Cerulenin, an antibiotic and antifungal, is an inhibitor of fatty acid biosynthesis; in vitro inhibition of HIV-1 proteinase. |
别名 | 浅蓝菌素;(2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide;Helicocerin |
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