| 应用 |
氟哌酸昌日本杏林公司1978年开发的第三代喹诺酮类抗菌剂。具有抗菌谱广、抗菌力强的特点。
Norfloxacin may be used as a standard in the determination of norfloxacin in human serum samples using fluorometric spectrophotometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| 产品介绍 |
类白色至淡黄色结晶性粉末。易溶于酸，碱溶液，极微溶于水和醇。无臭、味微苦。
熔点：227-228℃
Chemical structure: fluoroquinolone
Norfloxacin is a broad spectrum antibiotic, which is used against a wide variety of gram positive and gram negative bacteria. |
| 生化机理 |
Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase). Mode of action: inhibits bacterial DNA replication Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria |
| 别名 |
诺氟沙星;氟哌酸，1-乙基-6-氟-1,4-二氢-4-氧代-7-(1-哌嗪基)-3-喹啉羧酸;1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid |
