1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)-分析测试百科网

1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：3
近期咨询：0

分子式 C39H72O8PNa 分子量722.948 Beilstein号 EC号 MDL号 PubChem编号 24898361 属性存贮条件储存温度 -20°C //decorateTable('product-attribute-

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货号	CAS号	操作
D130369-100mg	108392-02-5	询底价
D130369-25mg	108392-02-5	询底价
D130369-500mg	108392-02-5	询底价

耗材描述

分子式 C₃₉H₇₂O₈PNa
分子量722.948
Beilstein号
EC号
MDL号
PubChem编号 24898361

属性

存贮条件	储存温度 -20°C

描述

应用	An activator of multiple PKC isotypes
产品介绍	Phosphatidic Acid, Dioleoyl has been shown to activate PKC α, ε, or ζ isotypes in the cytosol of COS cells. This compound not only stimulates PKC-ζ-mediated phosphorylation of distinctive substrates, but additionally causes an upward shift in electrophoretic mobility of PKC &zeta. Furthermore, experiments have reported Phosphatidic Acid to be generated by hydrolysis of phosphatidylcholine, via phospholipase D (PLD). Mechanistic studies suggest activation of PLD by insulin and consequential generation of Phosphatidic Acid which then induces Raf-1 translocation to cell membranes. Raf-1 is an essential component to the mitogen-activated protein kinase cascade, and once it has crossed over to the plasma membrane, other factors may activate it through phosphorylation.
别名	18:1 PA;1,2-二[顺式-9-十八碳烯酰基]-Sn-甘油-3-磷酸酯钠盐;18:1 PA;1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt;L-α-Phosphatidic acid, dioleoyl sodium salt

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