牛促肾上腺皮质激素释放激素-分析测试百科网

牛促肾上腺皮质激素释放激素

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品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：2
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分子式 C206H340N60O63S 分子量4697.33 MDL号 MFCD00081537 属性存贮条件储存温度:-20°C //decorateTable('product-attribute-specs-table') 描述

上海阿拉丁生化科技股份有限公司

上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
C118797-1mg	92307-52-3	询底价
C118797-5mg	92307-52-3	询底价

耗材描述

分子式 C₂₀₆H₃₄₀N₆₀O₆₃S
分子量4697.33
MDL号 MFCD00081537

属性

存贮条件	储存温度:-20°C

描述

产品介绍	氨基酸序列 Ser-Gln-Glu-Pro-Pro-Ile-S?er-Leu-Asp-Leu-Thr-Phe-Hi?s-Leu-Leu-Arg-Glu-Val-Leu?-Glu-Met-Thr-Lys-Ala-Asp-?Gln-Leu-Ala-Gln-Gln-Ala-H?is-Asn-Asn-Arg-Lys-Leu-Le?u-Asp-Ile-Ala Corticotropin Releasing Factor,bovine, (C206H340N60O63S1), a peptide with the sequence H2N-SQEPPISLDLTFHLLREVLEMTKADQLAQQAHNNRKLLDIA-amide, MW= 4697.4. Corticotropin-releasing hormone (CRH) also known as corticotropin-releasing factor (CRF) is a peptide hormone and neurotransmitter involved in the stress response. It belongs to corticotropin-releasing factor family(1). Its main function is the stimulation of the pituitary synthesis of ACTH.Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Increased CRH production has been observed to be associated with Alzheimer's disease and major depression(2), and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to being produced in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta, CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition.
生化机理	CRF是一种是由垂体前叶释放促肾上腺皮质激素和内啡肽的下丘脑肽。在中枢神经系统中它也是一种神经递质，涉及自主神经和内分泌对刺激的反应。
别名	CRF, CRH;CRF, CRH

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