耗材描述

• 分子式 C₁₉H₂₁N₅O₄·HCl
• 分子量419.87
• Beilstein号 4.30356e+006
• EC号 MFCD00058177
• MDL号 P160142
• PubChem编号

属性

熔点	285°C(lit.)
溶解性	H2O: 0.5 mg/mL，methanol: 6 mg/mL，dilute aqueous acid: insoluble.
存贮条件	储存温度-20°C

描述

应用	Prazosin hydrochloride has been used: · to block the α1adrenergic receptors that mediate sympathetic vasoconstriction in mice. · as an α1-adrenoceptor blocker,administered intragastrically in rats. · as a vasodilator,administered together with inuslin into the left ventricle of mice for the assessment of its effects on renal functions.
产品介绍	Prazosin hydrochloride (盐酸哌唑嗪)是α肾上腺素阻断剂，可作用于高血压、焦虑和恐慌症等
生化机理	Peripheral α1-adrenoceptor antagonist; vasodilator. Prazosin can be used to treat chronic posttraumatic stress disorder (PTSD). It plays a role in reducing blood pressure by relaxing blood vessels, hence used in the treatment of high blood pressure.
别名	盐酸哌唑嗪;脉哌斯;脲宁平;1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)-4-(2-呋喃甲酰)哌嗪盐酸盐;1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)-4-(2-呋喃甲酰基)哌嗪盐酸盐；脉宁平盐酸盐;1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine Hydrochloride

Reaxys-RN	4303561
信号词	Warning
危害声明	H302-H315-H319-H335-H361
警示性声明	P201-P261-P264-P280-P304 + P340 + P312-P308 + P313
个人防护设备	dust mask type N95 (US)， Eyeshields， Gloves
RTECS	VA1350000
WGK德国	3

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