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5-BrdU

CAS No. : 59-14-3

MCE 国际站：5-BrdU

产品活性：5-BrdU (BrdU) 是一种核苷类似物，可与胸苷竞争掺入 DNA。5-BrdU 通常用于检测增殖细胞。

研究领域：Cell Cycle/DNA Damage

作用靶点：Nucleoside Antimetabolite/Analog

In Vitro: Bromodeoxyuridine induces a progressive, dose-responsive suppression of cancer cell line and cancer stem cell population expansion RG2 rat glioma cells. In H9 cells and BJ fibroblasts, bromodeoxyuridine alters the cell cycle profile.?BrdU is stably integrated into the DNA, and thus can be used in assessment of cell proliferation and other cell procession.

In Vivo: Bromodeoxyuridine (300 mg/kg, i.p. or 0.8 mg/mL, p.o.) significantly slows tumor progression in rat glioma RG2 tumor model.

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