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Palmitoylethanolamide

CAS No. : 544-31-0

MCE 国际站：Palmitoylethanolamide

产品活性：Palmitoylethanolamide (Palmidrol) 是一种内源性活性化合物，可用于预防呼吸道病毒感染。

研究领域：Anti-infection  |  Metabolic Enzyme/Protease

作用靶点：Influenza Virus  |  Endogenous Metabolite

结构分类：其他类

In Vitro: Palmitoylethanolamide (Palmidrol) itself does not stimulate interferon production in mice treated per os or intravenously. But repeated application of this drug per os induces a macrophage activation, reflected by enhanced interferon production in vitro. When the interferon stimulation is delayed until 4 to 10 days after the first dose of Palmitoylethanolamide, interferon response to ds-RNA is slightly increased. After this phase of enhanced activity a decreased production of interferon is observed. Palmitoylethanolamide is not significantly effective in protecting mice from lethal dose of EMC virus. Application of this drug has an inhibitory effect on the toxicity of ds-RNA. A possible explanation of the mechanism by which Palmitoylethanolamide decreased the toxicity of virus in the organism is discussed.

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