MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Fagomine

CAS No. : 53185-12-9

MCE 国际站：Fagomine

产品活性：Fagomine 是一种温和的糖苷酶 (glycosidase) 抑制剂，Fagomine 作用于 Amyloglucosidase (A.niger)，β-Glucosidase (bovine) 和 Isomaltase (yeast)，K_i 分别为 4.8 μM，39 μM 和 70 μM。

研究领域：Metabolic Enzyme/Protease

作用靶点：Glucosidase

结构分类：糖类  |  单糖  |  结构分类

来源：植物  |  蓼科  |  荞麦

In Vitro: Fagomine (D-fagomine) is an iminosugar that has been shown to selectively agglutinate Enterobacteriales in vitro. Fagomine selectively agglutinates fimbriated enterobacteria (e.g., E.coli) and inhibits their adhesion to the intestinal mucosa; the reason for this is probably related to its structural similarity with lectin-binding saccharides (e.g., mannose). Fagomine is capable of altering this effect of high-fat high-sucrose diet (HFHS) on the proportion of Enterobacteriales and E.coli.

In Vivo: Fagomine (D-fagomine) is a natural iminosugar that counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales. Compare to the standard group, rats fed high-fat high-sucrose diet (HFHS) with Fagomine (D-fagomine) gain significantly less weight (15.3%) than those fed HFHS (20.9%).

相关产品：Natural Product Library Plus  |  Bioactive Compound Library Plus  |  Metabolism/Protease Compound Library  |  Natural Product Library  |  Anti-diabetic Compound Library  |  Medicine Food Homology Compound Library  |  Traditional Chinese Medicine Active Compound Library  |  Anti-Obesity Compound Library  |  Glucose Metabolism Compound Library  |  Food-Sourced Compound Library   |  Plant-Sourced Natural Product Library  |  Human Metabolite Library  |  Anti-Pulmonary Fibrosis Compound Library  |  Uvagrandol  |  EB-0156  |  α-Glucosidase-IN-15  |  Ambroxol hydrochloride  |  Kaempferol-7-O-rhamnoside  |  Lucidal  |  Afegostat D-Tartrate  |  IHVR-19029  |  Butyl isobutyl phthalate  |  Ganoderol B  |  Kojibiose  |  α-Glucosidase-IN-24  |  6-Prenylquercetin-3-Me ether  |  α-Glucosidase-IN-22  |  α-Homonojirimycin  |  NCGC00092410  |  Malabaricone B  |  4-Methylumbelliferyl β-D-Glucopyranoside  |  AMP-Deoxynojirimycin  |  ML198  |  Oroxin A  |  N-Nonyldeoxynojirimycin  |  Chrysophanol triglucoside  |  2-Nitrophenyl β-D-glucopyranoside  |  Celgosivir  |  α-Glucosidase-IN-14  |  β-Glucosidase  |  α-Glucosidase-IN-4  |  α-Glucosidase-IN-21  |  EB-0150

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

货号: HY-13005

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
•   专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。