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CCL9/10/MIP-1 gamma Protein, Mouse

MCE 国际站：CCL9/10/MIP-1 gamma Protein, Mouse

CCL9 Protein, Mouse，一种趋化因子，通常在巨噬细胞，破骨细胞中产生，并起细胞存活因子的作用。

Synonyms: rMuCCL9; C-C motif chemokine 9; Macrophage inflammatory protein 1-gamma; Small-inducible cytokine A9; Scya9; CCL9.

Species: Mouse

Source: E. coli

Biological Activity: The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 0.1-10 ng/mL.

研究背景：CCL9, a chemokine also known as macrophage inflammatory protein-1 gamma (MIP-1γ), is often produced in macrophages, osteoclasts, and functions as a cell survival factor. Among CC chemokine family members, the mouse CCL9 shares 45, 24, and 20% aa sequence identity with mouse CCL6 (C10), CCL3 (MIP-1α), and CCL4 (MIP-1β), respectively. CCL9/CCR1 signaling is important for the recruitment of myeloid progenitors to intestinal tumors, leading to enhanced invasion. CCL9 is highly induced in immature myeloid cells in the premetastatic lung of tumor-bearing mice or in co-culture with tumor cells, and it plays a critical role in tumor cell survival at the metastatic site.

蛋白编号：P51670 (Q22-Q122)

基因 ID：20308

产品分类：细胞因子和生长因子  |  趋化因子  |  CC 趋化因子  |  趋化因子 CCL9/CCL10

Categories：Cytokines and Growth Factors  |  Chemokine & Receptors  |  CC Chemokines  |  MIP-1 gamma/CCL9/CCL10

货号: HY-P7772

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