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PI-828

CAS No. : 942289-87-4

MCE 国际站：PI-828

产品活性：PI-828 是一种双重 PI3K 和 casein kinase 2 (CK2) 抑制剂，抑制 p110α，CK2 和 CK2α2，IC₅₀ 分别为 173 nM，149 nM 和 1127 nM。

研究领域：PI3K/Akt/mTOR  |  Stem Cell/Wnt  |  Cell Cycle/DNA Damage

作用靶点：PI3K  |  Casein Kinase

In Vitro: PI-828 (0.01-100 μM) exhibits cytotoxic effect on the 4T1 breast cancer cells and 4306 ovarian cancer cells.
PI-828 (0.78-3.12 µM; 48 hours) decreases caspase 3 activation; higher concentrations of PI-828 (6.25-12.5 μM) alone causes apoptosis.

相关产品：Bioactive Compound Library Plus  |  Cell Cycle/DNA Damage Compound Library  |  Kinase Inhibitor Library  |  PI3K/Akt/mTOR Compound Library  |  Stem Cell Signaling Compound Library  |  Wnt/Hedgehog/Notch Compound Library  |  Anti-Cancer Compound Library  |  Autophagy Compound Library  |  Anti-Aging Compound Library  |  Differentiation Inducing Compound Library  |  Oxygen Sensing Compound Library  |  Glycolysis Compound Library  |  Cytoskeleton Compound Library  |  Anti-Breast Cancer Compound Library  |  Anti-Lung Cancer Compound Library  |  Anti-Pancreatic Cancer Compound Library  |  Anti-Blood Cancer Compound Library  |  Anti-Cancer Metabolism Compound Library  |  Anti-Obesity Compound Library  |  Angiogenesis-Related Compound Library  |  Glucose Metabolism Compound Library  |  Anti-Liver Cancer Compound Library   |  Anti-Colorectal Cancer Compound Library   |  Anti-Prostate Cancer Compound Library  |  Anti-Pulmonary Fibrosis Compound Library  |  Cancer Stem Cells Compound Library  |  Pain-Related Compound Library  |  Membrane Protein-targeted Compound Library  |  Highly Selective Inhibitors Library  |  CK2-IN-4  |  Umbralisib hydrochloride  |  PI3K-IN-22  |  Rigosertib sodium  |  PI3Kδ/γ-IN-2  |  PI3kδ inhibitor 1  |  GSK2292767  |  PI3K-IN-28  |  PI3K/mTOR Inhibitor-13  |  Disitertide diammonium  |  1,3-Dicaffeoylquinic acid  |  Quercetin dihydrate  |  PI3Kγ inhibitor 4  |  4,5,6,7-Tetrabromo-1H-benzimidazole  |  PI-103 Hydrochloride  |  Hirsutenone  |  SN32976  |  Sophocarpine monohydrate  |  Heterophyllin B  |  IC-87114  |  Phosphatidylinositol 4,5-bisphosphate  |  JNJ-6204  |  Chaetominine  |  CK2-IN-1  |  PF-5006739  |  SF2523  |  TA-01  |  Ellagic acid  |  Flupentixol  |  EGFR-IN-57

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