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Sulcotrione

CAS No. : 99105-77-8

MCE 国际站：Sulcotrione

产品活性：Sulcotrione 是 β-三酮除草剂，可以抑制羟基苯基丙酮酸双加氧酶 (HPPD)。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease

作用靶点：Reactive Oxygen Species

In Vitro: The results show that sulcotrione behaves as time-independent reversible inhibitor. Similar results are previously described for natural β-triketones, and for the synthetic β-triketone NTBC. However it is the first time that such behavior is observed using a purified hydroxyphenylpyruvate dioxygenase (HPPD) and a synthetic β-triketone, namely sulcotrione. Inhibition kinetic analysis, performing with 3 hydroxyphenylpyruvate (HPP) and sulcotrione concentrations, show that the apparent K_M increasing with sulcotrione concentration. This behavior is consistent with the data present in the literature, describing sulcotrione as a competitive inhibitor of HPPD.

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